Sunday, October 16, 2011

Oxybutynine EG




Oxybutynine EG may be available in the countries listed below.


Ingredient matches for Oxybutynine EG



Oxybutynin

Oxybutynin hydrochloride (a derivative of Oxybutynin) is reported as an ingredient of Oxybutynine EG in the following countries:


  • France

  • Luxembourg

International Drug Name Search

Saturday, October 15, 2011

Déméclocycline




Déméclocycline may be available in the countries listed below.


Ingredient matches for Déméclocycline



Demeclocycline

Déméclocycline (DCF) is known as Demeclocycline in the US.

International Drug Name Search

Glossary

DCFDénomination Commune Française

Click for further information on drug naming conventions and International Nonproprietary Names.

Saturday, October 8, 2011

Oforta


Oforta is a brand name of fludarabine, approved by the FDA in the following formulation(s):


OFORTA (fludarabine phosphate - tablet; oral)



  • Manufacturer: SANOFI AVENTIS US

    Approval date: December 18, 2008

    Strength(s): 10MG [RLD]

Has a generic version of Oforta been approved?


No. There is currently no therapeutically equivalent version of Oforta available.


Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Oforta. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.




Related Patents


Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.




  • Oral fludara of high-purity formulation with quick release of active ingredient
    Patent 7,148,207
    Issued: December 12, 2006
    Inventor(s): Heil; Wolfgang & Tistam; Ulf & Lipp; Ralph & Tack; Johannes-Wilhelm
    Assignee(s): Schering Aktiengesellschaft
    This invention relates to a quick-release tablet formulation with >99.19% pure fludara (high-purity fludara) as an active ingredient in a defined composition of residual contaminants.
    Patent expiration dates:

    • December 20, 2022
      ✓ 
      Patent use: TREATMENT OF PATIENTS WITH B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
      ✓ 
      Drug product




  • Process for the production of fludarabine-phosphate lithium, sodium, potassium, calcium and magnesium salts and purification process for the production of fludarabine-phosphate and fludarabine-phosphate with a purity of at least 99.5%
    Patent 7,547,776
    Issued: June 16, 2009
    Inventor(s): Tilstam; Ulf & Schmitz; Thomas & Nickisch; Klaus
    Assignee(s): Bayer Schering Pharma Aktiengesellschaft
    The present invention generally relates to a fludarabine-phosphate with a purity of at least 99.5%.
    Patent expiration dates:

    • December 10, 2018
      ✓ 
      Drug substance



Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

  • Exclusivity expiration dates:
    • December 18, 2011 - NEW DOSAGE FORM

    • December 18, 2015 - ORPHAN DRUG EXCLUSIVITY

See also...

  • Oforta Consumer Information (Drugs.com)
  • Oforta Consumer Information (Wolters Kluwer)
  • Oforta Consumer Information (Cerner Multum)
  • Oforta Advanced Consumer Information (Micromedex)
  • Fludarabine Consumer Information (Wolters Kluwer)
  • Fludarabine Tablets Consumer Information (Wolters Kluwer)
  • Fludarabine Consumer Information (Cerner Multum)
  • Fludarabine injection Consumer Information (Cerner Multum)
  • Fludarabine Advanced Consumer Information (Micromedex)
  • Fludarabine Intravenous Advanced Consumer Information (Micromedex)
  • Fludarabine Phosphate AHFS DI Monographs (ASHP)

Thursday, October 6, 2011

Fluconazol Ardez




Fluconazol Ardez may be available in the countries listed below.


Ingredient matches for Fluconazol Ardez



Fluconazole

Fluconazole is reported as an ingredient of Fluconazol Ardez in the following countries:


  • Czech Republic

International Drug Name Search

Monday, October 3, 2011

Flutamida AC Farma




Flutamida AC Farma may be available in the countries listed below.


Ingredient matches for Flutamida AC Farma



Flutamide

Flutamide is reported as an ingredient of Flutamida AC Farma in the following countries:


  • Peru

International Drug Name Search

Monday, September 26, 2011

L-Adrenalin Fresenius




L-Adrenalin Fresenius may be available in the countries listed below.


Ingredient matches for L-Adrenalin Fresenius



Epinephrine

Epinephrine is reported as an ingredient of L-Adrenalin Fresenius in the following countries:


  • Austria

International Drug Name Search

bupivacaine liposome Injection


bue-PIV-a-kane LYE-poh-some


Commonly used brand name(s)

In the U.S.


  • Exparel

Available Dosage Forms:


  • Suspension

Therapeutic Class: Anesthetic, Local


Chemical Class: Amino Amide


Uses For bupivacaine liposome


Bupivacaine liposome injection is used to relieve pain after surgery. It belongs to the family of medicines called local anesthetics. bupivacaine liposome prevents pain by blocking the signals at the nerve endings


bupivacaine liposome is to be given only by or under the direct supervision of a doctor.


Before Using bupivacaine liposome


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For bupivacaine liposome, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to bupivacaine liposome or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of bupivacaine liposome injection in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bupivacaine liposome injection in the elderly. However, elderly patients are more likely to have kidney or liver problems, which may require caution for patients receiving bupivacaine liposome injection.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of bupivacaine liposome. Make sure you tell your doctor if you have any other medical problems, especially:


  • Bone or joint problems (e.g., chondrolysis)—May increase risk for more serious side effects.

  • Kidney disease or

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

  • Obstetrical paracervical block (numbing procedure)—Should not be used in patients having this procedure.

Proper Use of bupivacaine liposome


A nurse or other trained health professional will give you bupivacaine liposome in a hospital. bupivacaine liposome is given through a needle injected into the surgical site (such as big toe).


bupivacaine liposome should cause numbness only to the area where it is injected. You may experience temporary loss of sensation or motor skills to the area injected. This type of numbing procedure is called local anesthesia. It is not meant to cause you to fall asleep or become unconscious.


Bupivacaine liposome injection (Exparel™) works differently with other formulations of bupivacaine, even at the same dose (number of milligrams). Do not convert or change the dosing from any other formulations of bupivacaine to Exparel™.


Precautions While Using bupivacaine liposome


Your doctor will check you closely while you are receiving bupivacaine liposome. This is to check for any problems or unwanted effects that may be caused by bupivacaine liposome.


Tell your doctor or nurse right away if you have the following symptoms after receiving bupivacaine liposome: anxiety, blurred vision, depression, drowsiness, lightheadedness, nausea or vomiting, numbness and tingling of the mouth and lips, restlessness, ringing in the ears, speech problems, or tremors.


bupivacaine liposome may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; fever; increased sweating; lightheadedness or fainting; trouble breathing; trouble swallowing; or any swelling of your hands, face, mouth, or throat after receiving bupivacaine liposome.


bupivacaine liposome Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor or nurse immediately if any of the following side effects occur:


More common
  • Bloating or swelling of the face, arms, hands, lower legs, or feet

  • blurred vision

  • confusion

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • fast, pounding, or irregular heartbeat or pulse

  • fever

  • pale skin

  • rapid weight gain

  • sweating

  • tingling of the hands or feet

  • troubled breathing with exertion

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • unusual weight gain or loss

Less common
  • Bleeding from the anus

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chest pain or discomfort

  • fainting

  • lightheadedness, dizziness, or fainting

  • painful defecation

  • shortness of breath

  • slow or irregular heartbeat

  • swelling at the surgical site

Less common or rare
  • Chills

  • decrease in the frequency of urination

  • decrease in the urine volume

  • difficult or troubled breathing

  • difficulty in passing urine (dribbling)

  • extra heart beat

  • headache

  • hives

  • hoarseness

  • irregular, fast or slow, or shallow breathing

  • irritation

  • itching

  • joint pain, stiffness, or swelling

  • nervousness

  • not breathing

  • painful urination

  • pale or blue lips, fingernails, or skin

  • pounding in the ears

  • rash

  • redness of the skin

  • shakiness in the legs, arms, hands, or feet

  • shortness of breath

  • swelling at the incision site

  • tightness in the chest

  • troubled breathing or swallowing

  • weakness

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Back pain

  • muscle spasm

  • nausea

  • sleepiness or unusual drowsiness

  • sleeplessness

  • trouble sleeping

  • unable to sleep

  • vomiting

Less common
  • Decreased appetite

  • itching in the genital or other skin areas

  • scaling

  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Less common or rare
  • Agitation

  • cold sweats

  • hives or welts

  • increased sweating

  • muscle weakness

  • pain in the neck

  • paleness of the skin

  • restlessness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



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